After some trial and error, I seem to have finally found the right medication for my depression. I have been taking Trintellix for approximately 2 years now and I feel confident in saying it's working for me. It took a while, and we had to adjust the dosage, but now things have fallen into place. If you are reading this post, the most important thing I would like you to take away from this is NOT that Trintellix is a miracle drug and you have to run out to your doctor and ask for it immediately. My message is: don't give up. Keep trying, communicate openly with your health care provider, ask questions, describe your symptoms, share your notes and journals, follow up, follow through, give new options a fair try. Don't give up. Eventually you will find what's right for you.